Journal: Biomaterials
Article Title: Bone regeneration strategies: engineered scaffolds, bioactive molecules and stem cells Current stage and future perspectives
doi: 10.1016/j.biomaterials.2018.07.017
Figure Lengend Snippet: List of products associating bioactive molecules (growth factors, peptides or small molecules) with a material carrier and their stage of development. M: medical use; W: withdrawn; Phase I, II or III (P-I; P-II, P-III); TGA: therapeutic good administration; IDE: investigational device exemption. The countries are listed. COLL: collagen
Article Snippet: I-FACTOR™ peptide enhanced bone graft (Cerapedics, Inc.) is a composite bone graft material containing the P-15 peptide adsorbed onto calcium phosphate particles, which are suspended in a sodium carboxymethylcellulose hydrogel carrier.
Techniques: Cell Differentiation, Mutagenesis, Plasmid Preparation, Activation Assay